Nope.
All you’ll see is the message below; which should be worded entirely differently since you can’t choose a “different drive location”. Basically, it’s saying if you want to use it, reformat your Mac. 
Also, as far as I can see, there isn’t a workaround. Fucking Adobe. Oh, and Viva la HTML5.
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Josh Anderson's Blog 
AH HAHAHAHAAHAHA! You need to reverse engineer that motherfucker, change the code to stop the error coming up then make a shit load of aliases =D hehehe
Sorry still funny AH HAHAHAHAHAHA!
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Agreed man, I just formatted my mac so that I could EXPLICITLY use case sensitive filesystem features, and these pricks expect me to just deal with it?
Seriously, Fuck Adobe. I use to hate them, then Flex came out and I started not hating them as much. Now this I find out the hard way. Well fuck them. I’m glad I didn’t actually pay for this fucking garbage.
Totally crap – adobe are software developers from guiville these days. Get a computer programmer already.
I use to hate them, then Flex came out and I started not hating them as much. Now this I find out the hard way. Well fuck them. I’m glad I didn’t actually pay for this fucking garbage.
And they wonder why we set sail and pirate.
There is accauly a workaround. Fooling the installer into thinking it is on the startup disk when it is in a compatible drive… I am looking into that now. Mail me if you want details…
have you figured it out?
I would like details … how can we set this up so that i don’t have my email on here publicly
Someone know what to do with the case sensitive drive? Without reinstall?
Id like details please. I am experiencing this very problem. And I did pay for my software. did you figure it out by any chance?
Sito messaggio eccezionale. Ho intenzione di bookmark e controllare molto più spesso. Mi piace molto il modello di sito web
I like my case-sensitive file system. I don’t wanna change it because of a bunch of lazy programmers.
There is a way if you still need it.
https://bitbucket.org/lokkju/adobe_case_sensitive_volumes
and
http://arcticmac.home.comcast.net/~arcticmac/tutorials/cs5instructions.html.
Ignore the steps 5-7, 9, 10 and 12 from the first link.
Then, run the fix_case.pl script from the second link as mentioned. Now I have Photoshop CS5 running in my case sensitive partitions.
Best regards,
Lucas Timm